产品货号：
Z29925
中文名称：
CARD11抗体
英文名称：
Anti-CARD11 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CARD11 Antibody |
| 指标别名 | BIMP3;CARD11;Carma 1;CARMA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | CARD11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CARMA1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1.The immunogen is located within the last 50 amino acids of CARMA1. |
| 计算分子量 | 133kDa |
| 成分 | CARMA1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CARMA1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules.CARMA1,CARMA2,and CARMA3 share high degrees of sequence and functional homology,but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types.Both CARMA1 and CARMA3 associate with NEMO,the regulatory subunit of the I百K complex,thereby regulating activation of the NF-百B transcription factor.Also,gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS,indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems. |
| Uniprot ID | Q9BXL7 |
| 基因名全称 | Caspase recruitment domain family,member 11 |
| 蛋白名全称 | Caspase recruitment domain family,member 11 |
| 推荐稀释比 | CARMA1 antibody can be used for detection of CARMA1 by Western blot at 0.5 to 2μg/mL.A band at approximately 125kDa can be detected.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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